RAPAd®

    The RAPAd® method of Adenovirus construction, developed by ViraQuest Inc. scientists, has been used by other scientists around the world.

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    Confidentiality

     

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    Quality Control

    Plaque forming units guarantee. Non-detectable RCA.

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    Turnaround Time

    Sub-cloning to finished particles in about four weeks.

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    Dual Expressers

    Multiple transgene expression in a single virus.

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Tag Archives: Super Oxides

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance

Authors: Martínez-Sánchez N, Seoane-Collazo P, Contreras C, Varela L, Villarroya J, Rial-Pensado E, Buqué X, Aurrekoetxea I, Delgado TC, Vázquez-Martínez R, González-García I, Roa J, Whittle AJ, Gomez-Santos B, Velagapudi V, Tung YCL, Morgan DA, Voshol PJ, Martínez de Morentin PB, López-González T, Liñares-Pose L, Gonzalez F, Chatterjee K, Sobrino T, Medina-Gómez G, Davis RJ, Casals N, Orešič M, Coll AP, Vidal-Puig A, Mittag J, Tena-Sempere M, Malagón MM, Diéguez C, Martínez-Chantar ML, Aspichueta P, Rahmouni K, Nogueiras R, Sabio G, Villarroya F, López M.
Citation: Cell Metab. 2017 Jul 5;26(1):212-229.e12

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O 2⋅− and H 2 O 2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate

Authors: Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, Monga V, Bodeker KL, Ahmann L, Vollstedt S, Brown H, Kauffman EPS, Schall ME, Hohl RJ, Clamon GH, Greenlee JD, Howard MA, Schultz MK, Smith BJ, Riley DP, Domann FE, Cullen JJ, Buettner GR, Buatti JM, Spitz DR, Allen BG
Citation: Cancer Cell. 2017 Aug 14;32(2):268

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D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H 2 O 2- …

Authors: Sebastian J. Sciegienka, Shane R. Solst, Kelly C. Falls, Joshua D. Schoenfeld, Adrienne R. Klinger, Natalie L. Ross, Samuel N. Rodman, Douglas R. Spitz, Melissa A. Fath
Citation: Free Radic Biol Med. 2017 Jul; 108: 354–361

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Compositions and methods for cancer therapy

Authors: Bryan G. Allen, Douglas R. Spitz, Garry R. Buettner, Joseph Cullen, Joshua Schoenfeld, Michael Schultz, Fenghuang Zhan
Citation: Patent Application

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MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell

Authors: Tong Q, Zhu Y, Galaske JW, Kosmacek EA, Chatterjee A, Dickinson BC, Oberley-Deegan RE.
Citation: Free Radic Biol Med. 2016 Dec;101:32-43

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Overexpression of copper/zinc superoxide dismutase in the median preoptic nucleus improves cardiac function after myocardial infarction in the rat

Authors: Collister JP, Hartnett C, Mayerhofer T, Nahey D, Stauthammer C, Krüger M, Tobias A, O'Sullivan MG, Parker J, Tian J, Case AJ, Zimmerman MC.
Citation: Clin Exp Pharmacol Physiol. 2016 Oct;43(10):960-6

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Antitumoral gene-based strategy involving nitric oxide synthase type III overexpression in hepatocellular carcinoma

Authors: De la Rosa ÁJ, Rodríguez-Hernández Á, González R, Romero-Brufau S, Navarro-Villarán E, Barrera-Pulido L, Pereira S, Marín LM, López-Bernal F, Álamo JM, Gómez-Bravo MA, Padillo FJ, Muntané J.
Citation: Gene Ther. 2016 Jan;23(1):67-77

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Angiotensin II-induced hypertension is attenuated by overexpressing Copper/Zinc superoxide dismutase in the brain organum vasculosum of the lamina terminalis

Authors: John P. Collister, Heather Taylor-Smith, Donna Drebes, David Nahey, Jun Tian, and Matthew C. Zimmerman
Citation: Oxid Med Cell Longev. 2016;2016

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Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells

Authors: Okoh VO, Garba NA, Penney RB, Das J, Deoraj A, Singh KP, Sarkar S, Felty Q, Yoo C, Jackson RM, Roy D.
Citation: Br J Cancer. 2015 May 12;112(10):1687-702

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Spatial, temporal, and quantitative manipulation of intracellular hydrogen peroxide in cultured cells

Authors: Alim I, Haskew-Layton RE, Aleyasin H, Guo H, Ratan RR
Citation: Methods Enzymol. 2014;547:251-73

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