RAPAd®

The RAPAd® method of Adenovirus construction, developed by ViraQuest Inc. scientists, has been used by other scientists around the world.

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Confidentiality

 

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Quality Control

Plaque forming units guarantee. Non-detectable RCA.

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Turnaround Time

Sub-cloning to finished particles in about four weeks.

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Dual Expressers

Multiple transgene expression in a single virus.

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Tag Archives: Cancer

Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo.

Authors: Harvey TJ, Hennig IM, Shnyder SD, Cooper PA, Ingram N, Hall GD, Selby PJ, Chester JD.
Citation: Cancer Gene Ther. 2011 Nov;18(11):773-84. doi: 10.1038/cgt.2011.43.

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Re-expression of the methylated EDNRB gene in oral squamous cell carcinoma attenuates cancer-induced pain.

Authors: Viet CT, Ye Y, Dang D, Lam DK, Achdjian S, Zhang J, Schmidt BL.
Citation: Pain. 2011 Oct;152(10):2323-32.

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Distinct Redox Profiles of Selected Human Prostate Carcinoma Cell Lines: Implications for Rational Design of Redox Therapy

Authors: Luksana Chaiswing, , Weixiong Zhong, and Terry D. Oberley
Citation: Cancers 2011, 3(3), 3557-3584

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A probasin promoter, conditionally replicating adenovirus that expresses the sodium iodide symporter (NIS) for radiovirotherapy of prostate cancer.

Authors: Trujillo MA, Oneal MJ, McDonough S, Qin R, Morris JC.
Citation: Gene Ther. 2010 Nov;17(11):1325-32.

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Retargeted adenoviral cancer gene therapy for tumour cells overexpressing epidermal growth factor receptor or urokinase-type plasminogen activator receptor.

Authors: Harvey TJ, Burdon D, Steele L, Ingram N, Hall GD, Selby PJ, Vile RG, Cooper PA, Shnyder SD, Chester JD.
Citation: Gene Ther. 2010 Aug;17(8):1000-10.

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Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid.

Authors: Chu R, Zhao X, Griffin C, Staub RE, Shoemaker M, Climent J, Leitman D, Cohen I, Shtivelman E, Fong S.
Citation: Int J Cancer. 2010 Sep 1;127(5):1209-19.

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INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumors.

Authors: Wang HW, Breslin MB, Chen C, Akerstrom V, Zhong Q, Lan MS.
Citation: Hum Gene Ther. 2009 Nov;20(11):1308-18.

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Construction of an MUC-1 promoter driven, conditionally replicating adenovirus that expresses the sodium iodide symporter for gene therapy of breast cancer.

Authors: Trujillo MA, Oneal MJ, Davydova J, Bergert E, Yamamoto M, Morris JC 3rd.
Citation: Breast Cancer Res. 2009;11(4):R53.

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Image-guided radioiodide therapy of medullary thyroid cancer after carcinoembryonic antigen promoter-targeted sodium iodide symporter gene expression

Authors: Spitzweg C, Baker CH, Bergert ER, O'Connor MK, Morris JC
Citation: Hum Gene Ther 2007 Oct 18 10: 916-924

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