RAPAd®

The RAPAd® method of Adenovirus construction, developed by ViraQuest Inc. scientists, has been used by other scientists around the world.

Request Quote

Confidentiality

 

Learn More

Quality Control

Plaque forming units guarantee. Non-detectable RCA.

Learn More

Turnaround Time

Sub-cloning to finished particles in about four weeks.

Learn More

Dual Expressers

Multiple transgene expression in a single virus.

Learn More

Tag Archives: Cancer

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

Authors: Carotenuto M, Pedone E, Diana D, de Antonellis P, Džeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M
Citation: Sci Rep. 2013;3:1351

read more

Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure

Authors: Stancevic B, Varda-Bloom N, Cheng J, Fuller JD, Rotolo JA, García-Barros M, Feldman R, Rao S, Weichselbaum RR, Harats D, Haimovitz-Friedman A, Fuks Z, Sadelain M, Kolesnick R.
Citation: PLoS One. 2013 Aug 2;8(8):e69025

read more

Sodium iodide symporter (NIS)-mediated radiovirotherapy of hepatocellular cancer using a conditionally replicating adenovirus

Authors: Grünwald GK, Klutz K, Willhauck MJ, Schwenk N, Senekowitsch-Schmidtke R, Schwaiger M, Zach C, Göke B, Holm PS, Spitzweg C
Citation: Gene Ther. 2013 Jun;20(6):625-33

read more

EGFR-targeted adenovirus dendrimer coating for improved systemic delivery of the theranostic NIS gene

Authors: Grünwald GK, Vetter A, Klutz K, Willhauck MJ, Schwenk N, Senekowitsch-Schmidtke R, Schwaiger M, Zach C, Wagner E, Göke B, Holm PS, Ogris M, Spitzweg C.
Citation: Mol Ther Nucleic Acids. 2013 Nov 5;2:e131

read more

MEK1/2 inhibition elicits regression of autochthonous lung tumors induced by KRASG12D or BRAFV600E

Authors: Trejo CL, Juan J, Vicent S, Sweet-Cordero A, McMahon M
Citation: Cancer Res. 2012 Jun 15;72(12):3048-59

read more

MicroRNA‐194 is a target of transcription factor 1 (Tcf1, HNF1α) in adult liver and controls expression of frizzled‐6

Authors: Krützfeldt J, Rösch N, Hausser J, Manoharan M, Zavolan M, Stoffel M
Citation: Hepatology. 2012 Jan;55(1):98-107

read more

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

Authors: Rehman J, Zhang HJ, Toth PT, Zhang Y, Marsboom G, Hong Z, Salgia R, Husain AN, Wietholt C, Archer SL
Citation: FASEB J. 2012 May;26(5):2175-86

read more

Sodium Iodide Symporter (NIS)-Mediated Radionuclide ((131)I, (188)Re) Therapy of Liver Cancer After Transcriptionally Targeted Intratumoral in Vivo NIS Gene Delivery.

Authors: Klutz K, Willhauck MJ, Wunderlich N, Zach C, Anton M, Senekowitsch-Schmidtke R, G
Citation: Hum Gene Ther. 2011 Jun 28. [

read more

MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma.

Authors: de Antonellis P, Medaglia C, Cusanelli E, Andolfo I, Liguori L, De Vita G, Carotenuto M, Bello A, Formiggini F, Galeone A, De Rosa G, Virgilio A, Scognamiglio I, Sciro M, Basso G, Schulte JH, Cinalli G, Iolascon A, Zollo M.
Citation: PLoS One. 2011;6(9):e24584.

read more