RAPAd®

The RAPAd® method of Adenovirus construction, developed by ViraQuest Inc. scientists, has been used by other scientists around the world.

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Confidentiality

 

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Quality Control

Plaque forming units guarantee. Non-detectable RCA.

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Turnaround Time

Sub-cloning to finished particles in about four weeks.

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Dual Expressers

Multiple transgene expression in a single virus.

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Tag Archives: Cancer

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

Authors: Carotenuto M, Pedone E, Diana D, de Antonellis P, Džeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M
Citation: Sci Rep. 2013;3:1351

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Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure

Authors: Stancevic B, Varda-Bloom N, Cheng J, Fuller JD, Rotolo JA, García-Barros M, Feldman R, Rao S, Weichselbaum RR, Harats D, Haimovitz-Friedman A, Fuks Z, Sadelain M, Kolesnick R.
Citation: PLoS One. 2013 Aug 2;8(8):e69025

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Sodium iodide symporter (NIS)-mediated radiovirotherapy of hepatocellular cancer using a conditionally replicating adenovirus

Authors: Grünwald GK, Klutz K, Willhauck MJ, Schwenk N, Senekowitsch-Schmidtke R, Schwaiger M, Zach C, Göke B, Holm PS, Spitzweg C
Citation: Gene Ther. 2013 Jun;20(6):625-33

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EGFR-targeted adenovirus dendrimer coating for improved systemic delivery of the theranostic NIS gene

Authors: Grünwald GK, Vetter A, Klutz K, Willhauck MJ, Schwenk N, Senekowitsch-Schmidtke R, Schwaiger M, Zach C, Wagner E, Göke B, Holm PS, Ogris M, Spitzweg C.
Citation: Mol Ther Nucleic Acids. 2013 Nov 5;2:e131

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MEK1/2 inhibition elicits regression of autochthonous lung tumors induced by KRASG12D or BRAFV600E

Authors: Trejo CL, Juan J, Vicent S, Sweet-Cordero A, McMahon M
Citation: Cancer Res. 2012 Jun 15;72(12):3048-59

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MicroRNA‐194 is a target of transcription factor 1 (Tcf1, HNF1α) in adult liver and controls expression of frizzled‐6

Authors: Krützfeldt J, Rösch N, Hausser J, Manoharan M, Zavolan M, Stoffel M
Citation: Hepatology. 2012 Jan;55(1):98-107

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Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

Authors: Rehman J, Zhang HJ, Toth PT, Zhang Y, Marsboom G, Hong Z, Salgia R, Husain AN, Wietholt C, Archer SL
Citation: FASEB J. 2012 May;26(5):2175-86

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Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo.

Authors: Harvey TJ, Hennig IM, Shnyder SD, Cooper PA, Ingram N, Hall GD, Selby PJ, Chester JD.
Citation: Cancer Gene Ther. 2011 Nov;18(11):773-84. doi: 10.1038/cgt.2011.43.

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Re-expression of the methylated EDNRB gene in oral squamous cell carcinoma attenuates cancer-induced pain.

Authors: Viet CT, Ye Y, Dang D, Lam DK, Achdjian S, Zhang J, Schmidt BL.
Citation: Pain. 2011 Oct;152(10):2323-32.

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